7. Unexplained Weight Change

Cushing's syndrome can occur in some small-cell lung cancer patients, with which your body may be instructed to produce the hormone ACTH, which raises the level of cortisol, which can cause weight gain. On the other hand, SIADH, a hormone issue that affects your kidneys, and hypercalcemia both tend to make you lose your appetite, so you might start to lose weight without trying.

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